In a world where fertility rates have collapsed as a result of sexually transmitted diseases and environmental pollution, the totalitarian, theonomic government of Gilead establishes rule in the former United States in the aftermath of a civil war. Society is organized by power-hungry leaders along with a new, militarized, hierarchical regime of fanaticism and newly created social classes, in which women are brutally subjugated. By law, women in Gilead are forced to work in very limited roles, including some as natal slaves, and they are not allowed to own property, handle money, or read.
Worldwide infertility has led to the enslavement of fertile women in Gilead determined by the new regime to be "fallen women", citing an extremist interpretation of the Biblical account of Bilhah; these women often include those who have entered multiple marriages (termed "adulteresses"), single or unmarried mothers, lesbians (homosexuals being termed "gender traitors"), non-Christians, adherents of Christian denominations other than the Sons of Jacob, political dissidents and academics. These women, called Handmaids, are assigned to the homes of the ruling elite, where they must submit to ritualized rape (referred to as "the ceremony") by their male masters ("Commanders") in the presence of their wives, in order to become impregnated and bear children for them. Handmaids are given names created by the addition of the prefix Of- to the first name of the man who has them. When they are transferred, their names are changed accordingly.
Elisabeth Moss as June Osborne / Offred / Ofjoseph a woman
Joseph Fiennes as Commander Fred Waterford a high-ranking government official and June's former master
Yvonne Strahovski as Serena Joy Waterford Fred's wife and a former conservative cultural activist
Alexis Bledel as Dr. Emily Malek Ph.D. / Ofglen #1 / Ofsteven / Ofroy / Ofjoseph #1 June's shopping partner
Madeline Brewer as Janine Lindo / Ofwarren / Ofdaniel / Ofhoward a Handmaid
Ann Dowd as Aunt Lydia / Lydia Clements a woman in charge of overseeing the Handmaids in their sexual re-education and duties
Max Minghella as Commander Nick Blaine Commander Waterford's driver and a former drifter from Michigan
Samira Wiley as Moira Strand June's best friend since college
Amanda Brugel as Rita (main season 2 - present, recurring season 1), a Martha at the Waterford house
Bradley Whitford as Commander Joseph Lawrence (main season 3-present, recurring season 2), the founder of the Colonies and architect behind Gilead's economy
Sam Jaeger as Mark Tuello (main season 4, recurring season 2 - 3), an operative of the United States of America's government whom Serena encounters in Canada
Stephen Kunken as Commander Warren Putnam
Ever Carradine as Naomi Putnam Commander Warren Putnam's wife
Tattiawna Jones as Lillie Fuller / Ofglen #2 (seasons 1 - 2)
Nina Kiri as Alma / Ofrobert another Handmaid
Kristian Bruun as a Doctor in Gilead
Jenessa Grant as Dolores / Ofsamuel a local Handmaid with a friendly and talkative nature
Bahia Watson as Brianna / Oferic another local Handmaid
Jordana Blake as Hannah Bankole / Agnes MacKenzie June and Luke's daughter
Edie Inksetter as Aunt Elizabeth a fellow Aunt
Kristen Gutoskie as Beth (season 1, season 3-present), a chef before the rise of Gilead, formerly a Martha at Jezebel's
Erin Way as Erin a young, apparently mute, woman
Clea DuVall as Sylvia (season 2 - present), Emily's wife
Sydney Sweeney as Eden Blaine (nรฉe Spencer) (season 2), a pious and obedient girl
Cherry Jones as Holly Maddox (season 2 - present), June's mother, an outspoken feminist
Julie Dretzin as Eleanor Lawrence (seasons 2 - 3), the mentally unstable wife of Commander Lawrence
Greg Bryk as Commander Ray Cushing (season 2)
Rohan Mead as Isaac (season 2), a Guardian
Ashleigh LaThrop as Natalie / Ofmatthew (season 3), a devoted Handmaid whose loyalty to Gilead causes divisive tensions amongst her peers
Sugenja Sri as Sienna (season 3), a new Martha in the Lawrence household
O. T. Fagbenle as Luke Bankole June's husband from before Gilead
Jonathan Watton as Commander Matthew Calhoun (season 3), the assigned Commander of Natalie/Ofmatthew
Christopher Meloni as High Commander George Winslow (season 3), a High Commander stationed in Washington, D.C. He was killed in self-defense by June Osborne at Jezebels and his body was cremated by Marthas there
Elizabeth Reaser as Olivia Winslow (season 3), the wife of High Commander Winslow
Sarah McVie as Lena (season 3), a Swiss diplomat negotiating the hostile conflict between Gilead and Canada over Nichole
Jim Cummings as Burke (season 1), an Eye
Christian Barillas as Mr. Flores (season 1), Mrs. Castillo's assistant
Zabryna Guevara as Mrs. Castillo (season 1), an ambassador from Mexico
Rosa Gilmore as Zoe (season 1), the daughter of a US army soldier and the leader of the group of survivors whom Luke encounters after being separated from June and Hannah
Tim Ransom as Mr. Whitford (season 1), a friend of June's mother
Marisa Tomei as Mrs. O'Conner (season 2), a Commander's wife
Yahya Abdul-Mateen II as Omar (season 2), a man
John Carroll Lynch as Dan (season 2), Emily's boss at the university where she worked
Kelly Jenrette as Annie (season 2), Luke's ex-wife
Laila Robins as Pamela Joy (season 3), Serena Joy's mother
Amy Landecker as Mrs. MacKenzie (season 3), Hannah's placement mother in Gilead
Emily Althaus as Noelle (season 3), a young single mother whose son Aunt Lydia taught before the rise of Gilead
Rebecca Rittenhouse as Odette (season 2), a doctor and Moira's deceased fiancรฉe
Mckenna Grace as Mrs. Keyes (season 4), a farmer and the teenage wife of an older Commander
Angela Vint as Leah
Robert Curtis Brown as Andrew Pryce
Krista Morin as Rachel Tapping
Marissa Kate Wilson as Ofzachary's Partner
Paula Boudreau as Grace Williams
Birgitte Solem as Putnam Martha
Tasha Attey as Amber
Danielle Height as Meredith
Carson Manning as Marine Solider
Adrian Walters as Commander Horace
Victoria Fodor as Martha Cora
Chris Gillett as Commander Grinnell
Genevieve Adam as Wife #2
Ordena Stephens as Martha Frances
Brianne Tucker as Handmaid #1
Jamila Fleming as Handmaid C
Melissa Kelly as Fugitive Handmaid
Masa Lizdek as Sarah
Philip Craig as Maintenance Driver
Novie Edwards as Kit
Soo Garay as Fiona
Nicky Guadagni as Aunt Sarah
David Tompa as Mr. Spencer
Troy Blundell as Guardian #1
Helen King as Aunt Pauline
Vanessa Burns as Mrs. Calhoun
Shahi Teruko as Gwendolyn
Ashleigh Rains as Wife #1
Sarah Slywchuk as Handmaid
Ian Ronningen as Guardian
Jennie Raymond as Caroline
Elva Mai Hoover as Social Worker
Natalie Dale as Claire
Samantha Parkinson as Birthing Handmaid #2
Michelle Chiu as Birthing Handmaid #3
Joel Rinzler as Butcher
Raven Riley Duporte as Hannah (3 Years Old)
Jane Smythe as Wife
Alexandra Castillo as Dawn Mathis
Samer Salem as David
Gil Bellows as Doctor
John Ortiz as Jim Thorne
Ted Simonett as Older Guardian
Ben Lewis as Peter
Justin Landry as Pushy Job Seeker
Kim Roberts as Christine
Shane Daly as Joe Bradley
Damien Howard as Checkpoint Guardian
Ericka Kreutz as Nurse Wheeler
Deidrie Henry as Martha
Ian Ho as Ryan
Sadie Munroe as Rose
Marvin Kaye as Boat Captain
Christian Lloyd as Commander Guthrie
Ayomi Jonas as Hannah (4 Years Old)
Vas Saranga as Kyle
Ryan Turner as Uniformed Eye #1
Kirrilee Berger as Ofgeorge
Kirsten Johnson as Aunt
Deb Filler as Sally
Keeya King as Jenna
Daniel Malik as Uniformed Eye #2
Vanessa Matsui as Mrs. Tanaka
Asia Rempel as Young June
Diane Johnstone as Helen
Jake Mossop as Nurse
Kate Moyer as Kiki
Dan Beirne as Barista
Adrian Griffin as Commander Davidson
Tanya Faraday as Dee
Ian Geldart as Mike
Patrice Goodman as Doctor #3
Katie Messina as Carol
David Snelgrove as Eye Commander
Scott Baker as Jonathan
David Cotton as Guardian
Dรฉbora Demestre as Martha Reese
Kelsey Falconer as Ofandy
Ian MacPherson as Med Student
Gord Rand as Mattias
Evgeny Akimov as Commander
Lauren Horejda as Helen
Nicole Stamp as Lenore
Dave Lapsley as Executioner
Catherine McNally as Sarah
Tara Rosling as Sofia
Alex Spencer as DCBS Officer
Catherine Tait as Rose's Mother
Paniz Zade as Wanda
Michael Caruana as Roger
David Chinchilla as Guardian #1
Todd Thomas Dark as Commander Derek Chambers
Shruti Kothari as Woman with Moira
Ish Morris as Guardian Nurse
Charlie Riina as Handmaid
Bruce Tubbe as Matthew
Eilish Waller as Ofmyles
Amanda Barker as Tricia
James Gilbert as Stuart
Cornelia Luna as Unwoman #1
Danielle Ayow as Dr. Chung
Lindsey Connell as B&B Econo Mom
Melody Shang as Praying Martha #1
Katerina Taxia as Aunt Rebecca
Dylan Trowbridge as Daniel
Margaret Atwood as Aunt
Yvonne Gaudry as Female Worker #1
David Kirby as Commander Bennett
Cam Parkes as Young Guardian
Glen Schultz as Commander Glen Cooper
Nora Sweet-Underhill as Wife
Ricky Tollman as Putnam's Driver
Elise Bauman as Jenny
Sally Cahill as Roy's Wife
Michelle Hospedales as Holly's Friend #3
Carinne Leduc as Claudine
Ronica Sajnani as Unwoman #2
Heather Clark as Mel
Bobby Daniels as Guardian Technician
Caleb Ellsworth-Clark as Guardian #1
Sarah Mitchell as Praying Martha #2
Lara Mrkoci as School Security Guard
Evan Sabba as B&B Econo Dad
Toni Ellwand as Female Worker #2
Matthew Olver as Commander Monroe
Ryan Perlus as Surgeon
Natalie Turner as Call Girl
Adam Winlove-Smith as Guardian Prisoner
Josรฉ Arias as Kevin McConnell
Josephine Buettner as Unwoman #3
Lawrence Cotton as Commander Roy
Adrian Falconer as College Dean
Karen Glave as Dr. Hodgson
Jessica Greenberg as Holly's Friend #4
Valรฉrie Lecomte as Mrs. Spencer
Peggy Bree Tam as Punished Handmaid #1
Kevin Allan as Senior Guardian
Prince Amponsah as Cashier
Tom Barnett as Commander Logan
Catherine De Seve as Mrs. Allston
Krystle Ferdinand as Praying Econowife #1
Sarah Gale as Aunt Louise
Natalie Lisinska as Dr. Phillips
Melanie Phillipson as Martha Clara
Teagan Wright as B&B Econo Daughter
Christy Bruce as Emma Monroe
Josh Hehner as Assisting Surgeon
Mike Jackson as Commander
Caeden Lawrence as Guardian #1
Clark Backo as Genevieve
Lilly Bartlam as Eden's Sister
Allie Dunbar as Student Host
Andy McQueen as Dr. Epstein
Isaiah Rockcliffe as Adam
Diana Tso as Unwoman #4
Perrie Voss as Ofzachary
Cait Alexander as Jezebel
J. Adam Brown as Young Guardian
Yahsmin Daviault as June's Aunt
Scott Farley as Guardian Jeremiah
Emma Gibbs as Praying Econowife #2
Kathryn Greenwood as Martha Alison
Laura Hendrickson as Handmaid #4
Joel Lacoursiere as Staircase Guardian
William Poulin as Cambridge Priest
Matthew Rowsell as B&B Econo Son
Andrew Moodie as Mike Ahn
Dana Puddicombe as Econowife
Alastair Thorburn-Vitols as Young Singer
Karina Bradfield as Heckler #1
Joanna Douglas as Heather
Tim Gammon as Isaac's Father
Taylor Belle Puterman as Ashlyn
Steve Coombes as June's Guardian Escort
Heather Dicke as Staffer
Sava Drayton as Detention Security Guard
Natasha Araya Jimenez as Handmaid #5
Erica Levene as Prayer Circle Member #1
William Matthews as Checkpoint Guardian
Andrew McGillivray as Eye
Stephanie Ng Wan as Fearful Handmaid
Andrew Perun as Econo Husband Guest
Rebecca Singh as DC Station Aunt Guard
Kim DeLonghi as Isaac's Mother
Janelle Heron as Econowife
Nina Iordanova as Refugee
Nola Martin as Ashlyn's Mother
Felicia Simone as Crying Student
Luc Trottier as Heckler #2
Sandra Battaglini as Prayer Circle Member #2
Joanne Boland as Martha Maggie
Eric Craig as Post Ceremony Doctor
Seema Doad as Hurt Martha
Claudia Jurt as Red Center Aunt
Emma Laishram as Econo Wife Guest
Imali Perera as Martha Tamara
Naima Sundiata as Non-Veiled Handmaid
Jean Paul Najm as Guardian #1
Karen Robinson as Nurse Tania
Sehar Bhojani as Elise Watson
Richard Blackburn as Judge
Michala Brasseur as Caitlyn
David Gingrich as Linds
Jeff Ho as Bartender
Yasmijn Nicolle as Heckler #3
Ipsita Paul as Aunt Kimberly
Janet Pinnick as Ticket Agent
Beatriz Yuste as Neighbouring Martha #1
Jennifer Baker as Sheila Murray
Riley Gilchrist as Guardian #2
Jennifer Higgin as Prayer Circle Member #3
Daniel Jun as Billy
Stefanie Nakamura as Coat Check Woman
Maria Nash as Polly
Charlie Zeltzer as Oliver
Lisa Michelle Cornelius as UN Volunteer
Tosha Doiron as Nurse #1
Alex Frankson as Courthouse Tall Eye
Andy Auld as Lakehouse Driver
Roger Bainbridge as Paul Watson
Katherine Cullen as Neighbouring Martha #5
Myles Dobson as Supporter
Trevor Hayes as Pilot
Jason Jazrawy as I.C.E. Agent
Alana Pancyr as OfWyatt
Cornelia Walters as Protestor #1
Jenny Brizard as Escapee Martha
Ronin Harris as Micah
Karen Jewels as Karaoke Singer
Laurie Murdoch as Canadian Minister
Samy Osman as Eye #1
Alanis Peart as Optometrist
Kathleen Pollard as Prayer Circle Member #4
Elizabeth Whitmere as Martha Maureen
Thomas Hauff as Judge
Boomer Phillips as Eye
Bea Santos as Protester
Lesleh Donaldson as Neighbouring Martha #2
Alex Harrouch as Young Driver
Jonathan Malen as Quinn
James Smith as Protestor #5
Christopher Thompson as Gunman
Mark Wiebe as I.C.E. Supervisor
Lara Arabian as Prayer Circle Member #5
Julia Chantrey as Videographer
Lucy DiPucchio as Bloody Martha
Keisha T. Fraser as Bird Dog Protestor #1
Daveed Louza as CPS Agent
Thandie Quiambao as Sadie
Lisa Codrington as Officer #2
Bas Reitsma as Eye #2
Michael Wacholtz as Gambel
George Absi as American friend
Christina Collins as School Worker
Vicki Kim as Neighbouring Martha #3
Caitlin McConkey-Pirie as Girlfriend
Chris D'Silva as Tom
Sarah Marchand as Handmaid
Dani Pagliarello as Bird Dog Protestor #2
Stacy Smith as Prayer Circle Member #6
Kevin Whalen as Toronto Priest
Laura Wilson as Martha
Sam Asante as Ultrasound Tech
Michelle Bouey as American friend
Kevin Herod as Red Center Commander
Sacha Stewart as Neighbouring Martha #4
Andrew Zachar as Lakehouse Guardian
Alex Armbruster as Search Guardian
Raevv'n Leedham as Handmaid
Charlie Luborsky as Jonas
Spencer Robson as Brookline Guardian
Stephen Graham Simpson as Prayer Circle Member #7
Paul De La Rosa as Guardian Captain
Paul Beer as Doctor #2
Lili Connor as American friend
Lily Gao as Evelyn Chu
Jason Martorino as Prayer Circle Member #8
Michelle Mohammed as Handmaid
Helene Robbie as Mother
Mark Waters as Kiki's Father
Jay Davis as American friend
Maythaila Jerome Antoine as Handmaid
Catherine Huculak as Gilead Extra
Silvia Platsis as Gabrielle
Stuart Dowling as American Friend
Dominique Brownes as Ticona
Sachi Lovatt as Mother
Jacquelyn French as American friend
Deidre Cross as Mother
Donna Garner as American friend
Jenny Itwaru as Econowife #1
Mary Kelly as American friend
Anna Popowicz as Gilead Extra
Sophia Smith as Handmaid
David Lopez as American friend
Gita Galadauskaite as Econowife #3
Jordan Till as American friend
Ariel Lukane as Gilead Extra
Alisha Phillips as Gilead Extra
Kirsten Wendlandt as Econowife #6
Matthew Mease as Commander Father 1
Julian Osen as Gilead Extra
Nick Gough as Gilead Extra
Colin McClean as Gilead Extra
James Russell as Gilead Extra
Chris O'Bray as Gilead Extra
Greg Zajac as Gilead Extra
Charlie Hamilton as Gilead Extra
Yohance Thomas as Gilead Extra
Malakai Fox as Gilead Extra
Anne Yorke as Aunt #3
Katrina Parag as Girl #2
Rehan Suleman as Campus Officer
Gina Jun as Praying Martha
Megan Laursen as Handmaid
Sena Oztosun as Handmaid
Samantha Espie as Jean
David Thompson as Captured Guardian
Laura Vandervoort as Daisy
Kenny Wong as Lead Soldier
The average duration of each episode is 45 - 64 minutes. Country of origin: United States. Original language: English.