In a world where fertility rates have collapsed as a result of sexually transmitted diseases and environmental pollution, the totalitarian, theonomic government of Gilead establishes rule in the former United States in the aftermath of a civil war. Society is organized by power-hungry leaders along with a new, militarized, hierarchical regime of religious fanaticism and newly created social classes, in which women are brutally subjugated. By law, women in Gilead are forced to work in very limited roles, including some as natal slaves, and they are not allowed to own property, have careers, handle money, or read.
Worldwide infertility has led to the enslavement of fertile women in Gilead determined by the new regime to be fallen women, citing an extremist interpretation of the Biblical account of Bilhah. These women often include those who have entered multiple marriages (termed "adulteresses", as divorce is not recognised under Gileadian law), single or unmarried mothers, lesbians (homosexuals being termed "gender traitors"), non-Christians, adherents of Christian denominations other than the "Sons of Jacob", political dissidents, and academics.
These women, called Handmaids, are assigned to the homes of the ruling elite, where they must submit to ritualized rape (referred to as "the ceremony") by their male masters ("Commanders") in the presence of their wives, to be impregnated and bear children for them. Handmaids are given names created by the addition of the prefix Of- to the first name of the man who has them. When they are transferred, their names are changed.
Elisabeth Moss as June Osborne / Offred / Ofjoseph a woman
Joseph Fiennes as Commander Fred Waterford a high-ranking government official, and June's first master
Yvonne Strahovski as Serena Joy Waterford Fred's wife, and a former conservative cultural activist
Alexis Bledel as Dr. Emily Malek / Ofglen #1 / Ofsteven / Ofroy / Ofjoseph #1 (seasons 1 - 4), a former university lecturer in cellular biology and initially June's shopping partner
Madeline Brewer as Janine Lindo / Ofwarren / Ofdaniel / Ofhoward a Handmaid
Ann Dowd as Aunt Lydia Clements a woman in charge of overseeing the Handmaids in their sexual re-education and duties
Max Minghella as Commander Nick Blaine Commander Waterford's driver and a former drifter from Michigan
Samira Wiley as Moira Strand June's best friend since college
Amanda Brugel as Rita Blue (main season 2 - present, recurring season 1), a housekeeper at the Waterford house
Bradley Whitford as Commander Joseph Lawrence (main season 3 - present, guest season 2), the founder of the Colonies and architect of Gilead's economy
Sam Jaeger as Mark Tuello (main season 4 - present, recurring season 3, guest season 2), an operative of the U.S. Government whom Serena encounters in Canada
O. T. Fagbenle as Luke Bankole June's husband from before Gilead
Stephen Kunken as Commander Warren Putnam (season 1 - present), a high ranking official and the first known Commander of Janine
Ever Carradine as Naomi Putnam (season 1 - present), Commander Putnam's wife
Jordana Blake as Hannah Bankole (season 1 - present), June and Luke's daughter
Tattiawna Jones as Lillie Fuller
Nina Kiri as Alma / Ofrobert (seasons 1 - 4), another Handmaid
Bahia Watson as Brianna / Oferic (seasons 1 - 4), another local Handmaid
Jenessa Grant as Dolores / Ofsamuel (seasons 1 - 2, guest season 3), a local Handmaid with a friendly and talkative nature
Edie Inksetter as Aunt Elizabeth (season 1 - present), a fellow Aunt
Robert Curtis Brown as Commander Andrew Pryce (seasons 1 - 2), a Commander
Kristen Gutoskie as Beth (seasons 1 and 3, guest season 4), an award-winning chef before the rise of Gilead, formerly a Martha at Jezebel's, and later a Martha in the Lawrence household
Erin Way as Erin (seasons 1 - 3), a young, apparently mute woman
Krista Morin as Rachel Tapping (seasons 1 - 2, season 4), an official at the United States Consulate in Canada
Clea DuVall as Sylvia (season 2 - 3), Emily's wife
Sydney Sweeney as Eden Blaine (nรฉe Spencer) (season 2), a pious and obedient young girl
Cherry Jones as Holly Maddox (season 2 - 3), June's mother, an outspoken feminist
Greg Bryk as Commander Ray Cushing (season 2), a fellow Commander
Julie Dretzin as Eleanor Lawrence (seasons 2 - 3), the mentally unstable wife of Commander Lawrence
Rohan Mead as Isaac (season 2), a young Guardian assigned to the Waterford home
Ashleigh LaThrop as Natalie / Ofmatthew (season 3), a devoted Handmaid whose loyalty to Gilead causes divisive tensions amongst her peers
Sugenja Sri as Sienna (season 3, guest season 4), a new Martha in the Lawrence household
Jonathan Watton as Commander Matthew Calhoun (season 3 - present), the assigned Commander of Natalie/Ofmatthew
Charlie Zeltzer as Oliver (seasons 3 - 4), Emily and Sylvia's son
Christopher Meloni as High Commander George Winslow (season 3), a High Commander stationed in Washington, D.C
Elizabeth Reaser as Olivia Winslow (season 3), the wife of High Commander Winslow
Mckenna Grace as Esther Keyes (season 4 - present), a farmer and the teenage wife of an older Commander
Zawe Ashton as Oona (season 4), an aid worker in Toronto and Moira's new girlfriend
Jeananne Goossen as Aunt Ruth (season 4), a high ranking Aunt
Christine Ko as Lily (season 5), a former Martha
Genevieve Angelson as Gladys Wheeler (season 5), an affluent Canadian
Jim Cummings as Burke (season 1), an Eye
Christian Barillas as Mr. Flores (season 1), Mrs. Castillo's assistant
Zabryna Guevara as Mrs. Castillo (season 1), an ambassador from Mexico
Rosa Gilmore as Zoe (season 1), the daughter of a US army soldier and the leader of the group of survivors whom Luke encounters after being separated from June and Hannah
Tim Ransom as Mr. Whitford (season 1), a friend of June's mother
Marisa Tomei as Mrs. O'Conner (season 2), a Commander's wife
Yahya Abdul-Mateen II as Omar (season 2), a man
John Carroll Lynch as Dan (season 2), Emily's boss at the university where she worked
Deidrie Henry as Lori (seasons 3 - 4), a Martha
Sarah McVie as Lena (season 3), a Swiss diplomat negotiating the hostile conflict between Gilead and Canada over Nichole
Kelly Jenrette as Annie (season 2), Luke's ex-wife
Amy Landecker as Mrs. MacKenzie (season 3), Hannah's placement mother in Gilead
Laila Robins as Pamela Joy (season 3), Serena's mother
Rebecca Rittenhouse as Odette (season 2), a doctor, and Moira's deceased fiancรฉe
Emily Althaus as Noelle (season 3), a young single mother whose son Aunt Lydia taught before the rise of Gilead
Omar Maskati as Steven (season 4), the leader of a resistance group in Chicago
Reed Birney as Lieutenant Stans (season 4) a Gilead officer
Laura Vandervoort as Daisy (season 4), a Jezebels worker
Carly Street as Iris Baker/Aunt Irene (season 4), a former Aunt
Angela Vint as Leah
Marissa Kate Wilson as Ofzachary's Partner
Paula Boudreau as Grace Williams
Birgitte Solem as Putnam Martha
Tasha Attey as Amber
Danielle Height as Meredith
Kristian Bruun as Doctor
Adrian Walters as Commander Horace
Victoria Fodor as Martha Cora
Chris Gillett as Commander Grinnell
Genevieve Adam as Wife #2
Ordena Stephens as Martha Frances
Brianne Tucker as Handmaid #1
Jamila Fleming as Handmaid C
Masa Lizdek as Handmaid Fugitive 3
Philip Craig as Maintenance Driver
Sophia Walker as Abby
Allison Edwards-Crewe as Theresa
Nicky Guadagni as Aunt Sarah
Soo Garay as Fiona
Novie Edwards as Kit
Alexandra Castillo as Dawn Mathis
Melissa Kelly as Handmaid Fugitive 1
David Tompa as Mr. Spencer
Dรฉbora Demestre as Martha Reese
Victoria Goodman as Handmaid Fugitive 2
Troy Blundell as Guardian #1
Helen King as Aunt Pauline
Vanessa Burns as Mrs. Calhoun
Natasha Mumba as Danielle
Shahi Teruko as Gwendolyn
Victoria Sawal as Tyler
Ashleigh Rains as Wife #1
Sarah Slywchuk as Handmaid
Ian Ronningen as Guardian
Samer Salem as David
Amanda Zhou as Vicky
Bill MacDonald as Commander Keyes
Jennie Raymond as Caroline
Jasmin Husain as Ex-Handmaid
Elva Mai Hoover as Social Worker
Natalie Dale as Claire
Samantha Parkinson as Birthing Handmaid #2
Michelle Chiu as Birthing Handmaid #3
Joel Rinzler as Butcher
Raven Riley Duporte as Hannah (3 Years Old)
Jane Smythe as Wife
Sachi Lovatt as Handmaid 10
Gil Bellows as Doctor
John Ortiz as Jim Thorne
Nadeem Phillip as Pierre
Michael Ayres as Chris
Ted Simonett as Older Guardian
Eileen Li as Elena
Ben Lewis as Peter
Nona Parker Johnson as Darla
Sean Rey as Man
Kim Roberts as Christine
Justin Landry as Pushy Job Seeker
Alia Jackman as Woman
Shane Daly as Joe Bradley
Damien Howard as Checkpoint Guardian
Ericka Kreutz as Nurse Wheeler
Sadie Munroe as Rose
Ian Ho as Ryan
Malube Uhindu-Gingala as Mother
Marvin Kaye as Boat Captain
Christian Lloyd as Commander Guthrie
Vas Saranga as Kyle
Ryan Turner as Uniformed Eye #1
Ayomi Jonas as Hannah (4 Years Old)
Kirrilee Berger as Ofgeorge
Kat Khan as Hysterical Woman
Kirsten Johnson as Aunt
Vanessa Matsui as Mrs. Tanaka
Keeya King as Jenna
Daniel Malik as Uniformed Eye #2
Deb Filler as Sally
Asia Rempel as Young June
Kate Moyer as Kiki
Diane Johnstone as Helen
Jake Mossop as Nurse
Kenny Wong as Lead Soldier
Paloma Nuรฑez as Dr. Thomas
Timothy Ng as Video Tech
Dan Beirne as Barista
Adrian Griffin as Commander Davidson
Patrice Goodman as Doctor #3
Katie Messina as Carol
David Snelgrove as Eye Commander
Ian Geldart as Mike
Tanya Faraday as Dee
Gord Rand as Mattias
Kelsey Falconer as Ofandy
Scott Baker as Jonathan
David Cotton as Guardian
Ian MacPherson as Med Student
Massey Ahmar as Brad
Jailin Daley as Teen Soldier
Nicole Stamp as Lenore
Evgeny Akimov as Commander
Lauren Horejda as Helen
Catherine McNally as Sarah
Dave Lapsley as Executioner
Tara Rosling as Sofia
Paniz Zade as Wanda
Alex Spencer as DCBS Officer
Catherine Tait as Rose's Mother
Zaarin Bushra as Muslim Girl 1
Li Chen as Aide
Ish Morris as Guardian Nurse
Michael Caruana as Roger
David Chinchilla as Guardian #1
Charlie Riina as Handmaid
Shruti Kothari as Woman with Moira
Bruce Tubbe as Matthew
Todd Thomas Dark as Commander Derek Chambers
Eilish Waller as Ofmyles
James Gilbert as Stuart
Amanda Barker as Tricia
Cornelia Luna as Unwoman #1
Lindsey Connell as B&B Econo Mom
Dylan Trowbridge as Daniel
Katerina Taxia as Aunt Rebecca
Danielle Ayow as Dr. Chung
Melody Shang as Praying Martha #1
Kathy Imrie as Aunt Cordelia
Percy Harris as Official
Alicia Di Monte as Muslim Girl 2
Margaret Atwood as Aunt
Glen Schultz as Commander Glen Cooper
Yvonne Gaudry as Female Worker #1
Ricky Tollman as Putnam's Driver
Cam Parkes as Young Guardian
Nora Sweet-Underhill as Wife
David Kirby as Commander Bennett
Elise Bauman as Jenny
Ronica Sajnani as Unwoman #2
Carinne Leduc as Claudine
Sally Cahill as Roy's Wife
Michelle Hospedales as Holly's Friend #3
Sarah Mitchell as Praying Martha #2
Lara Mrkoci as School Security Guard
Caleb Ellsworth-Clark as Guardian #1
Bobby Daniels as Guardian Technician
Evan Sabba as B&B Econo Dad
Heather Clark as Mel
Fode Bangoura as Trader
Barrett Morrison as Gilead Soldier
Toni Ellwand as Female Worker #2
Adam Winlove-Smith as Guardian Prisoner
Matthew Olver as Commander Monroe
Ryan Perlus as Surgeon
Natalie Turner as Call Girl
Karen Glave as Dr. Hodgson
Josephine Buettner as Unwoman #3
Josรฉ Arias as Kevin McConnell
Adrian Falconer as College Dean
Valรฉrie Lecomte as Mrs. Spencer
Peggy Bree Tam as Punished Handmaid #1
Lawrence Cotton as Commander Roy
Jessica Greenberg as Holly's Friend #4
Natalie Lisinska as Dr. Phillips
Prince Amponsah as Cashier
Catherine De Seve as Mrs. Allston
Tom Barnett as Commander Logan
Kevin Allan as Senior Guardian
Krystle Ferdinand as Praying Econowife #1
Teagan Wright as B&B Econo Daughter
Sarah Gale as Aunt Louise
Melanie Phillipson as Martha Clara
Steve Boyle as MP Guardian
Christy Bruce as Emma Monroe
Caeden Lawrence as Guardian #1
Mike Jackson as Commander
Josh Hehner as Assisting Surgeon
Clark Backo as Genevieve
Lilly Noelle Bartlam as Eden's Sister
Andy McQueen as Dr. Epstein
Perrie Voss as Ofzachary
Isaiah Rockcliffe as Adam
Allie Dunbar as Student Host
Diana Tso as Unwoman #4
Cait Alexander as Jezebel
Kathryn Greenwood as Martha Alison
J. Adam Brown as Young Guardian
Scott Farley as Guardian Jeremiah
Yahsmin Daviault as June's Aunt
Emma Gibbs as Praying Econowife #2
Joel Lacoursiere as Staircase Guardian
William Poulin as Cambridge Priest
Matthew Rowsell as B&B Econo Son
Laura Hendrickson as Handmaid #4
James Blinkey as Driver
Andrew Moodie as Mike Ahn
Dana Puddicombe as Econowife
Alastair Thorburn-Vitols as Young Singer
Joanna Douglas as Heather
Taylor Belle as Ashlyn
Tim Gammon as Isaac's Father
Karina Bradfield as Heckler #1
Stephanie Ng Wan as Fearful Handmaid
Heather Dicke as Staffer
Sava Drayton as Detention Security Guard
Andrew Perun as Econo Husband Guest
Andrew McGillivray as Eye
Rebecca Singh as DC Station Aunt Guard
Steve Coombes as June's Guardian Escort
William Matthews as Checkpoint Guardian
Erica Levene as Prayer Circle Member #1
Natasha Araya Jimenez as Handmaid #5
Roderick McNeil as Farmhand 1
Jordin Hall as RCMP Officer
Kim DeLonghi as Isaac's Mother
Nola Martin as Ashlyn's Mother
Janelle Heron as Econowife
Felicia Simone as Crying Student
Luc Trottier as Heckler #2
Nina Iordanova as Refugee
Joanne Boland as Martha Maggie
Imali Perera as Martha Tamara
Claudia Jurt as Red Center Aunt
Seema Doad as Hurt Martha
Eric Craig as Post Ceremony Doctor
Sandra Battaglini as Prayer Circle Member #2
Naima Sundiata as Non-Veiled Handmaid
Emma Laishram as Econo Wife Guest
Marlon Palmer as Security Guardian
Tejay McDonald as Farmhand 2
Karen Robinson as Nurse Tania
Jean Paul Najm as Guardian #1
Michala Brasseur as Caitlyn
Ipsita Paul as Aunt Kimberly
Beatriz Yuste as Neighbouring Martha #1
Sehar Bhojani as Elise Watson
Richard Blackburn as Judge
Janet Pinnick as Ticket Agent
David Gingrich as Linds
Yasmijn Nicolle as Heckler #3
Jeff Ho as Bartender
Daniel Jun as Billy
Jennifer Higgin as Prayer Circle Member #3
Maria Nash as Polly
Stefanie Nakamura as Coat Check Woman
Jennifer Baker as Sheila Murray
Riley Gilchrist as Guardian #2
Jamillah Ross as Jezebel's Martha
Tara Redmond van Rees as Kylie
Luke Aquilina as Guardian 1
Roland Greber as Security Officer
Lisa Michelle Cornelius as UN Volunteer
Tosha Doiron as Nurse #1
Alex Frankson as Courthouse Tall Eye
Trevor Hayes as Pilot
Alana Pancyr as OfWyatt
Katherine Cullen as Neighbouring Martha #5
Jason Jazrawy as I.C.E. Agent
Myles Dobson as Supporter
Andy Auld as Lakehouse Driver
Roger Bainbridge as Paul Watson
Cornelia Walters as Protestor #1
Elizabeth Whitmere as Martha Maureen
Laurie Murdoch as Canadian Minister
Jenny Brizard as Escapee Martha
Samy Osman as Eye #1
Kathleen Pollard as Prayer Circle Member #4
Alanis Peart as Optometrist
Karen Jewels as Karaoke Singer
Ronin Harris as Micah
Craig Burnatowski as Barber
Wayne Davis as Raymond Lomas
Jane Hailes as Doctor
Bea Santos as Protester
Boomer Phillips as Eye
Thomas Hauff as Judge
Jonathan Malen as Quinn
Alex Harrouch as Young Driver
Lesleh Donaldson as Neighbouring Martha #2
Mark Wiebe as I.C.E. Supervisor
Christopher Thompson as Gunman
James Smith as Protestor #5
Julia Chantrey as Videographer
Lara Arabian as Prayer Circle Member #5
Daveed Louza as CPS Agent
Lucy DiPucchio as Bloody Martha
Keisha T. Fraser as Bird Dog Protestor #1
Thandie Quiambao as Sadie
David Thompson as Jonathan Pogue - Captured Guardian
Samantha Espie as Jean
Al McFoster as Bailiff
Lisa Codrington as Officer #2
Bas Reitsma as Eye #2
Michael Wacholtz as Gambel
Vicki Kim as Neighbouring Martha #3
Christina Collins as School Worker
Caitlin McConkey-Pirie as Girlfriend
George Absi as American friend
Kevin Whalen as Toronto Priest
Dani Pagliarello as Bird Dog Protestor #2
Sarah Marchand as Handmaid
Chris D'Silva as Tom
Stacy Smith as Prayer Circle Member #6
Jane Luk as Presiding Judge
Luxton Handspiker as Asher
Laura Wilson as Martha
Andrew Zachar as Lakehouse Guardian
Sam Asante as Ultrasound Tech
Michelle Bouey as American friend
Sacha Stewart as Neighbouring Martha #4
Kevin Herod as Red Center Commander
Raevv'n Leedham as Handmaid
Alex Armbruster as Search Guardian
Spencer Robson as Brookline Guardian
Charlie Luborsky as Jonas
Stephen Graham Simpson as Prayer Circle Member #7
Janelle Hutchison as Aunt Wendy
Paul De La Rosa as Guardian Captain
Lili Connor as American friend
Paul Beer as Doctor #2
Lily Gao as Evelyn Chu
Helene Robbie as Mother
Michelle Mohammed as Handmaid
Mark Waters as Kiki's Father
Jason Martorino as Prayer Circle Member #8
Jay Davis as American friend
Silvia Platsis as Gabrielle
Maythaila Jerome Antoine as Handmaid
Catherine Huculak as Gilead Extra
Stuart Dowling as American Friend
Dominique Brownes as Ticona
Jacquelyn French as American friend
Deidre Cross as Mother
Donna Garner as American friend
Jenny Itwaru as Econowife #1
Mary Kelly as American friend
Sophia Slaysman as Handmaid
Anna Popowicz as Gilead Extra
David Lopez as American friend
Gita Galadauskaite as Econowife #3
Jordan Till as American friend
Ariel Lukane as Gilead Extra
Alisha Phillips as Gilead Extra
Kirsten Wendlandt as Econowife #6
Matthew Mease as Commander Father 1
Julian Osen as Gilead Extra
Nick Gough as Gilead Extra
Colin McClean as Gilead Extra
James Russell as Gilead Extra
Chris O'Bray as Gilead Extra
Greg Zajac as Gilead Extra
Charlie Hamilton as Gilead Extra
Yohance Thomas as Gilead Extra
Malakai Fox as Gilead Extra
Anne Yorke as Aunt #3
Shannon Heron as Child Bride
Rehan Suleman as Campus Officer
Katrina Parag as Girl #2
Sena Oztosun as Handmaid
Megan Laursen as Handmaid
Drew Catherine as Lesbian 1
Matthew MacFadzean as Doctor
Feaven Abera as Housekeeper
The average duration of each episode is 41 - 65 minutes. Country of origin: United States. Original language: English.